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Chronic discoid lupus erythematosus and systemic lupus erythematosus in adults and; Treatment of acute and persistent rheumatoid arthritis in adults. plaquenil Although each medication cross the placenta, they don’t have any notable effects on the fetus.The main unwanted side effects of hydroxychloroquine are described in the product info.Cardiotoxic results are rare however severe problems of hydroxychloroquine, which include acute cardiac conduction problems have also been noticed.Important interactions embrace use with tamoxifen, proton pump inhibitors, and with smoking.The primary property of those medicine contribute to their ability to build up in lysosomes.They have a large volume of distribution within the blood and a half-lifetime of days. plaquenil Drug data contained herein could also be time sensitive. Multum's drug info doesn't endorse medication, diagnose sufferers or advocate therapy. 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